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Studies & Results

BCIRG 103

A PreSurgical Study to Evaluate Molecular Alterations That Occur in Human Breast Cancer Tissue and Normal Skin After Short Term Exposure to ZD1839 (IRESSA) and to Correlate These Alterations With Pharmacokinetic Parameters

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Presentations

San Antonio Breast Cancer Symposium, 2006

Finn R

Results of BCIRG 103: A presurgical study to evaluate molecular alterations that occur in human breast cancer tissue after short-term exposure to gefitinib.

San Antonio Breast Cancer Symposium, 2006

Finn RS, Dering J, Ginther C, et al

Expression of EGFR ligands betacellulin and tenascin C are associated with molecular response following gefitinib treatment in women with primary breast cancer.

ASCO Annual Meeting, 2006

Finn RS, Dering J, Ginther C, et al

ER+ PR- breast cancer defines a unique subtype of breast cancer that is driven by growth factor signaling and may be more likely to respond to EGFR targeted therapies.

For information on any of TRIO's clinical trials, please contact Valérie Bee, Director Project Management at valerie.bee@trioncology.org